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The majority of these reports have occurred in patients concomitantly receiving other medications that suppress the immune system, which may also contribute to HBV reactivation
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6 GLP-1 receptor-positive cells have been identified in human retinal ganglion cells (RGCs), which could suggest a direct protective effect of these medications at the site of damage
While GLP-1RAs have been linked to a statistically significant elevation in the risk of early-stage DR events compared to placebo, they may conversely demonstrate a protective effect against the progression to advanced-stage diabetic retinopathy when compared to insulin therapy [81]